An efficient approach of conjugated tetraenes from butadiene and alkynes

Conjugated tetraenes are important key substructures in electronic materials, natural products and pharmaceutical molecules. However, they are difficult to synthesize. Now, researchers in Japan have achieved a new synthetic route of conjugated tetraenes from inexpensive and easily available 1,3-butadiene and substituted acetylenes by a one-pot approach under mild conditions.

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